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S., and about 5,000 are permanently affected by it.

It can occur in both sexes, though is more common in men.

Symptoms that may occur include: a painful or burning sensation when urinating, an unusual discharge from the penis, testicular pain or swelling, or fever.

If left untreated, chlamydia in men can spread to the testicles causing epididymitis, which in rare cases can lead to sterility if not treated.

At present, the NAATs have regulatory approval only for testing urogenital specimens, although rapidly evolving research indicates that they may give reliable results on rectal specimens.

Because of improved test accuracy, ease of specimen management, convenience in specimen management, and ease of screening sexually active men and women, the NAATs have largely replaced culture, the historic gold standard for chlamydia diagnosis, and the non-amplified probe tests.

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Of those who have an asymptomatic infection that is not detected by their doctor, approximately half will develop pelvic inflammatory disease (PID), a generic term for infection of the uterus, fallopian tubes, and/or ovaries.Long-term cohort studies indicate that approximately 50% of those infected clear within a year, 80% within two years, and 90% within three years.Persistent organisms remain viable as they are capable of returning to a normal growth state once conditions in the host cell improve.There is much debate as to whether persistence has in vivo relevance.Many believe that persistent chlamydiae are the cause of chronic chlamydial diseases.

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